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Using an Epinephrine Auto-Injector: How to Care for Your Child

Epinephrine is a first-aid medicine for serious allergic reactions (anaphylaxis). This medicine is easy to carry and use. Your child should have two epinephrine auto-injectors available at all times.

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Your health care provider prescribed epinephrine because your child is at risk for a life-threatening allergic reaction, called anaphylaxis. Epinephrine comes in an auto-injector. There are different types of auto-injectors, such as EpiPen® and Auvi-Q®.

Your child should use an epinephrine auto-injector right away if symptoms of a serious allergic reaction develop. Symptoms may include:

  • trouble breathing, swallowing or speaking

  • tightness in the throat

  • swollen tongue or lips

  • a hoarse voice

  • wheezing

  • coughing

  • vomiting

  • feeling lightheaded or fainting

  • many hives on different parts of the body or widespread redness

  • a combination of two mild symptoms, like a few hives with nausea 

Here are some things to keep in mind about epinephrine auto-injectors:

  • Fill the prescription for the auto-injectors right away.

  • Epinephrine auto-injectors usually come in a two-pack. Keep both auto-injectors together because your child should have two epinephrine auto-injectors nearby at all times. This is in case one injector does not work or your child needs another dose of epinephrine before help arrives in an emergency.

  • Your health care provider may prescribe extra sets of epinephrine auto-injectors to keep at school, at home, and with your child.

  • Store the medicine away from light (for example, in a small bag) and at room temperature. Do not refrigerate the epinephrine and do not allow it to get hot.

  • Check the expiration date on the auto-injectors regularly. If any injector is about to expire, call your health care provider to have the prescription refilled.

  • Check the liquid in the epinephrine auto-injectors once a month. To do this, look in the small window on the auto-injector. The liquid in the epinephrine auto-injectors should be clear. If the fluid is colored or cloudy, or if it contains particles, call your health care provider to have the prescription refilled.

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To use an epinephrine auto-injector:

  1. If possible, lay your child down. If not, have your child sit down.

  2. Remove the auto-injector from its case.

  3. Remove the safety release cap(s).

  4. Firmly grasp the auto-injector in your hand. Keep your fingers and thumb away from both ends of the injector.

  5. If you have A pen-shaped auto-injector (EpiPen® or generic):

    • Hold your child's leg still, and use a swinging motion to firmly push the orange or red end of the auto-injector into the middle of your child's outer thigh until you hear a click. (You do not need to remove your child's clothes. The needle can go through clothing.)

    • Follow the auto-injector's instructions on how long to hold the device in place (for example, an EpiPen® is held for 3 seconds, but some generic injectors are held for 10 seconds), then remove. Massage the thigh area for 10 seconds.

  6. OR if you have: An Auvi-Q®:

    • Place the black end against the middle of your child's outer thigh and press firmly so that you hear a click. (You do not need to remove your child's clothes. The needle can go through clothing.)

    • Hold the Auvi-Q® in place for 2 seconds, then remove.

  7. Call 911 and tell them your child is having a life-threatening emergency.

  8. If your child is not already lying down, lay him or her down and raise the legs.

  9. If symptoms do not start to improve in 5 minutes, use a second auto-injector. If symptoms improve after the first dose, but return while waiting for the ambulance, use a second auto-injector. Follow the same steps listed above.

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  • You are not sure how or when to use the epinephrine auto-injector.

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  • Epinephrine was given to your child. Your child may have a second wave of symptoms. Take the used epinephrine auto-injector to the hospital with you.

  • You or your child is injected in the hand or foot with epinephrine by accident.

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